DEP, mesotherapy

 

 

 

• DEP (Dermoelectroporation®)non-invasive transdermal drug delivery system called superconducting mesotherapy is actually somewhat misleading, because mesotherapy therapy is only one of the functions of the DEP  As a new generation of non-invasive needle-free percutaneous injection instrument developed by MATTIOLI Engineering, a famous Italian medical laser company. DEP uses current transmission and vibration through the current pulse flowing through the extracellular matrix to direct the long-chain glycosaminoglycans to produce aquaporins (aquaporins, “pores” formed by proteins in the cell membrane) and allow the ionized substance passes through the epidermis layer of the skin and is absorbed into the dermis and sarcolemma, without changing the state and PH value of the drug, ensuring that the effective ingredients are not damaged. It can effectively replace the invasive injection method, avoid pain, scabbing, sensitivity, scaling, itching and pigmentation problems and risks in the inflammatory phase, and there is no recovery period.

 

 

• Smear-type mesotherapyneedle: It is a kind of skin care product that looks like an injection in the outer packaging, but is actually a skin care product that is directly applied to the face. The name of the mesotherapy makes you associate with various effects. No wounds, but the active ingredients are also difficult to penetrate the skin barrier for the body to absorb.

 

• Skin boosteruses an injection-type instrument to directly inject the “active ingredient” into the skin between the epidermis and the dermis. Mesotherapy acupuncture is an invasive project. The needle port is an open wound that can bleed. It must be performed under strict aseptic operation, otherwise infection or inflammation may easily occur. The current mesotherapy needle instruments generally use a micro-needle array to control the injection dose and the depth of skin penetration to achieve the best effect. Because it is an invasive project, the process is not comfortable, and it is not very friendly to people with low pain tolerance or needle phobia, although anesthesia can be applied.

Since the injection can maximize the absorption of the injection by the skin, if the drug is formulated properly, the skin improvement effect can be expected.

 

• The needle-free mesotherapymachine uses high-speed airflow (subsonic speed of 850Kpa/sec) to push the liquid medicine. The nutrient solution is atomized by the high-speed airflow and shoots towards the skin, forming a pit on the surface of the skin. The skin is stretched and the epidermis is formed. Thinning, the spaces between cells are stretched, and nutrients are pushed into the interior of the skin. However, only by forcibly injecting nutrients into the skin through the pressure of high-speed airflow, the injection depth can only reach the basal layer of the epidermis, and the injection depth is limited, and the amount of nutrients entering the skin will also be limited.

Compared with the injection-type mesotherapy, the needle-free mesotherapy is slightly less effective, and the impact of air flow will also make people with sensitive skin feel uncomfortable, but it is better than non-invasive, and the process is relatively comfortable.